Looking into the Black Box of Synaptic Vesicle Recruitment

P81: Evaluating the Function of Motoneuron-Like Cells Differentiated from Rat Adipose Derived Stem Cells through Voltage-Sensitive Dyes (Rh 795) and Investigating the Synaptic Vesicle Recycling

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Evaluation of H-reflex recruitment curve after application of TENS on the desensitised skin of vertebral column

Electrical stimulation of neuromuscular system has been used in a variety of research and therapeutic applications. Although tri-polar transcutaneous electrical stimulation (TENS) is commonly used to change motoneuron excitabi1ity, but the effect of TENS on synaptic activities through dorsal column stimulation or cutaneous pathways is unknown. So, the aim of this research study was to determine...

Looking into the Black Box of Strategic Activities: an Activity Theoreti Cal Perspective

Localized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors.

Activity-dependent changes in presynaptic function represent a critical mechanism by which synaptic strength is controlled. However, how changes in synaptic activity couple to presynaptic components to control synaptic vesicle release and recycling are poorly understood. Sphingosine kinase (SphK) is a sphingolipid metabolic enzyme whose activity-dependent recruitment to membrane regions within ...

Involvement of actin polymerization in vesicle recruitment at the calyx of Held synapse.

Depletion and replenishment of pools of synaptic vesicles are important determinants of short-term synaptic plasticity, but the underlying molecular mechanisms are not yet clear. As a first step toward understanding the process of vesicle recruitment, we have applied various specific agents directly to the presynaptic terminal of the calyx of Held synapse. Here we show that the nonhydrolyzable ...